Being fat makes prostate cancer deadlier: every two and a half stone increases risk by 10%

Hundreds of British men could be saved from prostate cancer each year if they lost weight, a large study suggests.

Experts from the University of Oxford looked at measurements of more than 2.5 million men.

Each five-point increase in BMI – about 2.5 (35 lbs) for the average British man – was associated with a 10 percent greater chance of dying from prostate cancer.

Five points is enough to take someone from a healthy weight to overweight or overweight to obese.

The researchers estimate that bulging waistlines are responsible for 1,300 deaths from prostate cancer in Britain each year.

Prostate cancer is the most common cancer in men in the UK, with around 52,000 diagnoses per year. In the US, about 165,000 are diagnosed, with nearly 30,000 deaths.

Every five point increase in body mass index (BMI) – equivalent to about 2.5 stones in the average British man – increases the risk of death from prostate cancer by 10 percent

dr. Aurora Perez-Cornago and colleagues said: ‘We found that men with higher total and central adiposity have a higher risk of dying from prostate cancer than men of a healthy weight.

‘Knowing more about factors that increase the risk of prostate cancer is essential to prevent it.

“Age, family history and black ethnicity are known risk factors, but they can’t be changed, so it’s important to discover risk factors that can potentially be changed.”

Adequate sleep is crucial to maintain weight, study shows

Sleeping at least six hours a night is crucial to keeping your weight under control, according to a study today.

Researchers from the University of Copenhagen in Denmark spent a year studying the duration and quality of sleep in nearly 200 obese adults.

People who slept less than six hours a night saw their BMI score increase by 1.3 points after one year, compared to those who slept more than six hours.

More than a third of adults in the UK and US sleep less than six or seven hours a night due to stress, screens and the blurring of work-life boundaries.

The study, presented at the European Congress on Obesity (ECO) in Maastricht, the Netherlands, followed 195 adults after eight weeks of dieting.

The participants had a BMI between 32 and 43 before the start of the study and lost an average of 12 percent body fat.

They were then followed for a year, with accelerometers used to measure sleep before and after the diet and at weeks 13, 26 and 52.

Those who slept more than six hours were better able to maintain their weight gain than those who slept less than that amount.

Similarly, poor sleepers—as measured by a self-rated questionnaire—raised their BMI score by 1.2 points after one year compared to good sleepers.

The scientists found that about two hours of vigorous physical activity per week can help you sleep better.

Lead author Adrian Bogh, a biomedicine student, said: “It was surprising to see how losing weight in obese adults improved sleep duration and quality in such a short time, and how exercising while trying to keep the weight off led to improvements in preserved sleep quality. †

“It was also intriguing that adults who don’t get enough sleep or sleep poorly after weight loss seem less successful at maintaining weight loss than people who get enough sleep.”

She said several biological reasons for the increased risk have been suggested, although the disease may be harder to detect in obese men, meaning it’s diagnosed at a later stage, when it’s more difficult to treat.

dr. Perez-Cornago added: ‘More research is needed to determine whether the association is biologically driven or due to delays in detection in men with higher adiposity.

“In either case, our latest results provide another reason for men to try and maintain a healthy weight.”

The findings were presented today at the European Congress on Obesity in Maastricht, the Netherlands, and published simultaneously in the journal BMC Medicine.

Simon Grieveson, from Prostate Cancer UK, said: ‘This large-scale study suggests that being overweight is associated with an increased risk of dying from prostate cancer.

“While these results are compelling, more research is needed to fully understand the biological relationship between obesity and prostate cancer and, most importantly, how we can use this information to improve outcomes for men.”

“Maintaining a healthy weight can protect against many cancers, but it’s important to remember that prostate cancer can affect men of all shapes and sizes.

“Men over 50, black men, and men with a family history are most at risk for the disease and should see their doctor if they’re concerned.”

Researchers kept the men’s medical records for an average period of about 12 years.

Men were between 40 and 69 years old and no cancer had been diagnosed at the start of the study.

At the end of the follow-up period, 661 died from the disease.

Their BMI scores, body fat percentages, waist circumference and waist-to-hip ratios were recorded to see how these affected cancer development and severity.

Using statistical analysis, the team found that a higher waist circumference and waist-to-hip ratio increased the risk of death with prostate cancer.

Those in the top quarter for both measurements had a 25 percent greater risk of dying from the disease than those in the bottom quarter.

Every extra 10 cm (3.9 in) on a man’s waist increased his chance of dying from prostate cancer by 7 percent.

But a higher percentage of body fat had no effect on the risk of death, the data showed.

The average height of an adult male in the UK is about 177.8cm (5ft 10in) and the average weight is 13th 3lbs (83.9kg), suggesting that a five point lower BMI would equate to 2.5th ( 16 kg) weight loss.

A separate study presented at congress claimed that sleeping at least six hours a night is crucial to keeping your weight in check.

Researchers from the University of Copenhagen in Denmark spent a year studying the duration and quality of sleep in nearly 200 obese adults.

People who slept less than six hours a night saw their BMI score increase by 1.3 points after one year compared to those who slept more than six hours.

More than a third of adults in the UK and US sleep less than the sixth or seven hours a night because of stress, screens and the blurring of work-life boundaries, studies have shown.

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