Stanford Medicine magazine examines what molecules reveal about us and our health | news center

“Indeed, Stanford’s fundamental scientists have made extraordinary contributions to biomedicine,” Lloyd Minor, MD, dean of the School of Medicine, said in a letter in the issue. “Their hard-earned discoveries often open up whole new fields. And with each progress they are forging new avenues for future discoveries.”

The problem includes:

An article describing how the move from medical school to the Stanford University campus led Stanford medical students, researchers and physicians to join forces with high-tech powerhouses to accelerate molecular discoveries that could revolutionize the way medicine is practiced.

· A look at how cryogenic electron microscopy increases our understanding of diseases and how to treat them.

· A sample of a dozen Stanford Medicine researchers about their favorite molecules revealing what amazes them about their tiny subjects.

The story of how two researchers discovered that circles of free-floating DNA, or extrachromosomal DNA, help cancerous tumors evade treatment in some patients, a revelation that has made scientists re-watch these culprits hiding in plain sight

· An exploration of new thinking about pain, starting with the concept that not everyone feels pain in the same way. In this article, Stanford Medicine pain experts discuss the approaches they use to individualize pain remedies, ranging from designing new drugs to developing online pain management classes to assessing the usefulness of psychedelics.

A story about how a mother’s decision to donate her daughter’s tumor for research after she died of a rare brain cancer opened the door to cancer immunotherapy.

· An article describing the link between neurotransmission and excessive mucus secretion – which can cause serious illness in some – and how exploiting those similarities could lead to a solution.

The problem also looks at neuroscientist Sergiu Pasca’s pioneering development of a cell culture method that allows scientists to watch parts of a human brain develop and form connections in real time, ushering in a new era of brain science; an effort driven by a cadre of black women to create a peer navigation program for black women with breast cancer; and the perspective of psychologist Keith Humphreys, president of the StanfordLancet Commission on the Opioid Crisis, calling on several groups to work together to put patients first in tackling the crisis.

Stanford Medicine magazine is available both online at stanmed.stanford.edu and in print. Printed copies of the new issue will be sent to subscribers. Others can request a copy by emailing [email protected]

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